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Chronic Lyme Disease: Understanding, Diagnosing, and Treating the Hidden Illness - Part 1

Updated: Jan 23


Chronic Lyme disease is one of the most misunderstood and elusive conditions in the world of healthcare. Caused by the bacteria Borrelia burgdorferi, Lyme disease is transmitted through the bite of infected black-legged ticks. In its early stages, Lyme disease can often be treated with a simple round of antibiotics. However, in many cases, the disease goes undiagnosed or inadequately treated, leading to chronic Lyme disease, which can wreak havoc on the body and mind. This series will explore the complexities of chronic Lyme disease, how conventional testing often fails to diagnose it, and what can be done to help those suffering from it.


What Is Chronic Lyme Disease?

Chronic Lyme disease is a long-term, persistent illness caused by Borrelia bacteria that, if not properly treated, can linger in the body and cause a wide array of debilitating symptoms. While Lyme disease is often associated with joint pain and a "bull's-eye" rash, chronic Lyme manifests much differently and can affect multiple systems in the body, including the nervous system, immune system, cardiovascular system, and digestive system.

Some of the most common symptoms of chronic Lyme disease include:

  • Fatigue and exhaustion

  • Muscle and joint pain

  • Brain fog or cognitive difficulties

  • Headaches and migraines

  • Digestive issues

  • Heart palpitations

  • Sleep disturbances

  • Anxiety and depression


The persistence of symptoms in chronic Lyme disease may be due to the bacteria's ability to evade the immune system and linger in tissues, where it continues to cause ongoing damage. Unfortunately, diagnosis and treatment can be complicated due to the variable nature of the disease and the ability of the bacteria to "hide" in the body.


How Conventional Testing Fails to Diagnose Chronic Lyme Disease

One of the biggest challenges in diagnosing chronic Lyme disease is that conventional testing often fails to detect the infection, especially in its later stages. Most of the commonly used tests, such as the ELISA (enzyme-linked immunosorbent assay) test and the Western blot test, focus on detecting antibodies to Borrelia in the blood. However, these tests have limitations, particularly when it comes to diagnosing chronic or persistent infections.

  1. Timing of the Test: The most well-known Lyme disease tests measure antibodies, such as IgM and IgG, which are produced by the immune system in response to infection. However, these antibodies may not be present in the early stages of infection, which can lead to false negatives. Even after the infection has become chronic, the bacteria can "hide" in tissues, making it difficult for the immune system to produce detectable levels of antibodies.

  2. The Problem with IgM and IgG Testing: Conventional Lyme tests often focus on detecting IgM (an early antibody) and IgG (a long-term antibody) responses. However, IgM responses can diminish over time, leaving only IgG antibodies. This means that someone with chronic Lyme may show a positive IgG test but a negative IgM test, which can be misleading.

  3. False Negatives: Standard Lyme tests are notorious for producing false-negative results, especially in cases of chronic Lyme. This is due to several factors, including the bacteria's ability to evade the immune system, changes in the bacteria's outer proteins, and the limitations of the tests themselves. As a result, individuals who are suffering from Lyme disease may not receive a diagnosis despite having the disease for years.

  4. Inadequate Sensitivity: The conventional tests often lack the sensitivity needed to detect Lyme disease in its chronic form. The body may not produce enough antibodies in response to the infection, or the bacteria may be hiding in tissues where they are not easily detected. As a result, patients may receive negative test results even though they are experiencing a range of symptoms related to Lyme disease.


Stay tuned for Part 2 & Stay Vibrant and Well-Nourished, Friends!


Disclaimer: Please note that the information provided in this post is for educational purposes only and should not be construed as medical advice. It is not intended to diagnose, treat, cure, or prevent any disease. Additionally, while nutrients play a vital role in supporting overall health, not all nutrients are suitable for all individuals. Before making any changes to your diet or supplementation regimen, it's essential to consult with a qualified healthcare professional, especially if you have any underlying health conditions or are taking medications. Always prioritize your health and well-being by seeking personalized guidance from a healthcare provider.

 
 

© 2025 Colleen DeSimone

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